HISTONE LYSINE DEMETHYLASE JMJD2D/KDM4D AND FAMILY MEMBERS MEDIATE EFFECTS OF CHRONIC SOCIAL DEFEAT STRESS ON MOUSE HIPPOCAMPAL NEUROGENESIS AND MOOD DISORDERS

Depression, anxiety and related mood disorders are major psychiatric illnesses worldwide, and chronic stress appears to be one of the primary underlying causes.Therapeutics to treat these debilitating disorders without a relapse are limited due to the incomplete molecular understanding of their etiopathology.In addition to the well-studied genetic

The article presents the examination of three generations of a family with diagnosed left ventricular noncompaction (LVNC) and various phenotypic manifestations of the disease (isolated, Parasols hypertrophic and dilated type of LVNC).As a result of a molecular genetics tests, a previously undescribed single nucleotide deletion in the PRDM16 gene w

Turtle shell dorsal armor comprises a typical lightweight laminated composite structural material, which is constructed by cuticle and bone layer, with high specific strength and high fracture toughness.The red-eared slider turtle, a widely studied species of turtle, has a rich hierarchical structure.In this paper, according to the structure of red

ABSTRACT Trans/plurilingual theory and pedagogies have been generating extensive attention within global English language teaching and teacher education.This article responds to the burgeoning area of trans/plurilingual pedagogies, outlining diverse pedagogical practices and perspectives from a group of English language educators at a large, cosmop

The non-invasive inspection of surfaces is a major issue in a wide variety of industries and research laboratories.The vast and increasing range of surface types, tolerance requirements and measurement constraints demanded during the last decades represents a major research effort in the development of new methods, systems and metrological strategi